The "key" to acute hepatitis Liver biopsies from transplanted children The causes of acute hepatitis in children are being sought scientists are trying to identify
More data on the causes of acute hepatitis in children will be available in the coming days from Britain, which has the highest number of cases. Professor of Paediatrics, Ioanna Pavlopoulou, noted that none of the known hepatitis A,B,C,D,E, are associated with acute hepatitis in children with a poor clinical presentation, and stressed that more data will be available from liver biopsies in children who have had transplants in the UK.
Speaking to ERT, Ms. Sonidou said that in the UK "out of 160 cases of acute hepatitis, 10 children needed a transplant. All are in good health they were not at risk and there was no human casualty."
"Children who have contracted coronavirus in the UK are only at 16%," she said, so "we cannot attribute to this the increase in cases of acute hepatitis from January2022."
Adenovirus 41 the most likely cause
He said "75% of children hospitalised with severe hepatitis had adenovirus 41″, that is where we have attributed the increase in cases" but as he explained "we are not sure yet" and added that "none of the known hepatitis A,B,C,D,E have been identified so they are not linked to the acute hepatitis we observed in the children with the poor clinical presentation".
On whether the problem of acute hepatitis can extend to the age of the children, Professor of Pediatrics Ioanna Pavlopoulou clarified that "we are talking about ages from a few months to 16 years. The good news is that these cases of acute hepatitis are rare. Until the day before yesterday, according to WHO records, there are 200, with most in the UK. The worrying thing is that an unusually high proportion need a liver transplant."
To look at the underlying factor
He stressed that "we need to look at the children who are more severely ill to see if there is an underlying factor, immunological or otherwise, that predisposes them to having this severe progression" and estimated that "we will have more data from the UK in the coming days, regarding liver biopsies as well."
To parents he advised "If a child has gastrointestinal symptoms (vomiting, diarrhoea, abdominal pains) that do not improve, or fever and jaundice they should contact their paediatrician."
To parents he advised "If a child has gastrointestinal symptoms (vomiting, diarrhoea, abdominal pains) that do not improve, or fever and jaundice they should contact their paediatrician.
Source: in.gr
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