Specifically, the Cyprus Atherosclerosis Society (CSA) welcomes the recent publication of its members in the internationally renowned and high impact[/B] (IF:24) Journal of the American Academy of Cardiology entitled "Arterial Ultrasound Testing to Predict Atherosclerotic Cardiovascular Events" (J Am Coll Cardiol.2022;79:1969-1982) and congratulates its members, Prof. Andreas Nicolaides, Dr. Andri Panagiotou, Niki Georgiou and Dr. Efthyvoulos Kyriakou, as well as the entire research team.
As mentioned, the article concerns an analysis of data from the Cyprus Epidemiological Study on Atherosclerosis, a prospective epidemiological study in people over 40 years old, which involved 985 volunteers with a 17-year follow-up.
Participants were measured ultrasonographically for the presence and size of atherosclerotic plaques in four main arteries, two carotid and two femoral. The published data highlight the prognostic value of using atherosclerosis imaging techniques in both carotid and significantly in femoral arteries beyond traditional risk factors for the risk of cardiovascular events.
Themain findings presented are that two-dimensional ultrasound imaging of subclinical atherosclerotic plaque size significantly improved the prognosis for cardiovascular events beyond that of traditional risk factors, and the extent of subclinical atherosclerotic disease (ie, the number of arteries with atherosclerosis) was also associated with an increased risk for cardiovascular events.
Furthermore, the predictive value of the presence of subclinical atherosclerosis in the femoral artery is greater than the presence of carotid atherosclerosis, and the predictive value of quantifying atherosclerosis in the femoral artery (plaque area and maximum thickness) is greater than measurement of intima-media thickness (IMT). These results, it is noted, further support the value of screening more arterial substrates for atherosclerosis and significantly validate a critical concept, namely that atherosclerosis is a systemic disease.
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