Around the world there are now about 190 cases of severe hepatitis in children, according to the European Centre for Disease Prevention and Control (ECDC).
The outbreak was first reported in the UK earlier this month and has been identified in at least 12 countries around the world. This includes around 40 cases in the European Union/European Economic Area, ECDC chief Andrea Amon told reporters at an online briefing today.
The ECDC is investigating these cases alongside national authorities and the World Health Organization.
As of 1 January 2022, 114 cases of acute hepatitis of undetermined etiology have been recorded in children under the age of 16 in Britain. Yesterday, a report by the British health authorities was made public regarding the progress and developments in the investigation of unclear-cause acute hepatitis in children.
The data of a new report from Britain
As Elias Mosialos states in presenting the report, the hypotheses of the British researchers in order from most to least likely) with the current data are as follows:
1. Some - still unclear - factor affecting young children that either makes adenovirus infections more severe than usual or causes the immunopathology in question. This enhancing factor may be
A. Susceptibility, for example due to lack of previous exposure to the pathogen during the pandemic
B. previous coronavirus or other infection
C. dual/concurrent infection e.g. with coronavirus
D. exposure to toxin(s), drugs or other environmental factors
2. A novel variant of adenovirus, with or without a contribution from an enhancing agent
3. A novel pathogen that either acts alone or as a concomitant infection
4. A new variant of coronavirus
Source: in.gr
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